• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza

Coronavirus Update: In accordance with the order from the South Carolina Governor's Office, our dining room will be temporarily closed. However, WE ARE OPEN and offering awesome curbside and take-out options. Please note our temporary hours. Be safe, Beaufort.

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, delicious panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.

In addition to great dining, Panini's on The Waterfront is very proud to call itself one of the best banquet facilities in Beaufort South Carolina. We are well-known for providing the best services for many event planners and individuals. Our dedicated and committed team of event coordinators would love to help you plan your perfect reception in Beaufort.


FREE DELIVERY to Downtown Businesses

Panini's Free Delivery We appreciate our local downtown businesses and understand that lack of staffing can make it difficult to get out for lunch. We are now offering FREE DELIVERY to downtown businesses located from New Castle to Cateret & Bay to Craven from 11am-4pm, Tuesday-Saturday. Call (843) 379-0300.  Read More →

Curbside and Take-Out - All of Your Panini's Favorites

Panini's Take Out OrdersTake Out, Don't Break Out. Don't let the World around you ruin your appetite! We invite you to order your Panini's favorites TO-GO! Panini's makes it easy for customers to place to-go orders directly from our website or Facebook. Scroll through the menu to find all your Panini's lunch and dinner favorites. Just click or call ahead and leave the cooking to us.   Read More →