• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza


Live Music

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, delicious panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.


In addition to great dining, Panini's on The Waterfront is very proud to call itself one of the best banquet facilities in Beaufort South Carolina. We are well-known for providing the best services for many event planners and individuals. Our dedicated and committed team of event coordinators would love to help you plan your perfect reception in Beaufort.




Give the Gift of Great Taste with a Gift Card from Panini's

Paninis Gift Cards Looking for the perfect gift this holiday? Give the gift of great taste! A Panini’s Gift Card makes the perfect stocking-stuffer. Share the Panini's on The Waterfront experience with someone special this holiday season! The right gift gard can help you show your appreciation with one simple gesture.Your friends, family, co-workers, employees, or clients will love the gift of lunch, brunch, or dinner and drinks at one of the best restaurants in Beaufort.  Read More →

Panini's Wreaths Across America Fundraiser

Wreaths Across AmericaJoin us Tuesday, November 19th, 4pm - 9pm to break bread, raise your glass, and enjoy a fun time with friends as we raise money for "Wreaths Across America". With your support, we'll be able to purchase and place wreaths this holiday season at Beaufort National Cemetery Veterans graves. Locally, our US Military Vets M/C Beaufort is charged with coordinating this wonderful project.  Read More →