• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza

Open with Extended Covid-19 Precautions

Join us inside or on the River Deck. We're taking additional safety precautions for your dining experience in downtown Beaufort.

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, delicious panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.

In addition to great dining, Panini's on The Waterfront is very proud to call itself one of the best banquet facilities in Beaufort South Carolina. We are well-known for providing the best services for many event planners and individuals. Our dedicated and committed team of event coordinators would love to help you plan your perfect reception in Beaufort.


Thanksgiving Dinner 2020

Thanksgiving dinner Come celebrate Thanksgiving with a wonderfully prepared, traditional Thanksgiving Day meal at Panini’s on the Waterfront. Our beautiful downtown Beaufort location makes the perfect place to spend Thanksgiving with family and friends. Along with our full regular menu, we're serving a traditional smoked Thanksgiving Turkey Platter with all the trimmings. Open from 11 AM until the last seating at 3:30 PM (closed at 4 PM). Reservations are not necessary.  Read More →

Panini's is Committed to Your Safety

Palmetto Priority On October 2, 2020, the South Carolina's Governor's Office ordered most precautions concerning Covid-19 with restaurants to be lifted. While we appreciate the opportunity to start to get back to normal, we also recognize the need to continue to keep our patrons and staff safe (over and beyond the Governor's order). Until further notice, the team at Panini's on the Waterfront will continue to help guard against Covid-19 by maintaining reduced occupancy, practicing social distancing, and (staff) wearing masks.   Read More →