• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.

​Get in the Holiday Spirit at A Night on the Town in Historic Beaufort, SC

Paninis A Night on the Town Beaufort Panini’s on the Waterfront is excited about getting in the holiday spirit! It’s one of our favorite times of the year because we get to celebrate with you! Come on out on Friday December 4th for the 30th Annual “A Night on the Town” in beautiful downtown Beaufort, SC. and prepare for the holiday festivities!  Read More →

Spend Thanksgiving Day With Us at Panini’s on the Waterfront

Thanksgiving at Paninis If you’re not in the mood to cook this Thanksgiving but want a delicious traditional holiday meal, we’d like to invite you to join us at Panini’s on the Waterfront in beautiful downtown Beaufort, SC. We are happy to announce that we will be serving a traditional Thanksgiving Day dinner at Panini’s from 11am to 4pm, with the last reservation/seating at 3:30pm.  Read More →