• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza


Live Music

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, delicious panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.


In addition to great dining, Panini's on The Waterfront is very proud to call itself one of the best banquet facilities in Beaufort South Carolina. We are well-known for providing the best services for many event planners and individuals. Our dedicated and committed team of event coordinators would love to help you plan your perfect reception in Beaufort.




New Year's Brunch in Your PJ’s

New Year’s Day BrunchJoin us on January 1st, 2020, 11am to 3pm, to get the New Year started right! We will be hosting our annual old fashioned “Come As You Are” New Year’s Brunch, and we’d love to see you here! Along with our regular menu, we'll have our Breakfast Buffet loaded with all of your favorites for $16.95 per person.   Read More →

Give the Gift of Great Taste with a Gift Card from Panini's

Paninis Gift Cards Looking for the perfect gift this holiday? Give the gift of great taste! A Panini’s Gift Card makes the perfect stocking-stuffer. Share the Panini's on The Waterfront experience with someone special this holiday season! The right gift gard can help you show your appreciation with one simple gesture.Your friends, family, co-workers, employees, or clients will love the gift of lunch, brunch, or dinner and drinks at one of the best restaurants in Beaufort.  Read More →