• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza


live music beaufort nightlife

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, delicious panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.


In addition to great dining, Panini's on The Waterfront is very proud to call itself one of the best banquet facilities in Beaufort South Carolina. We are well-known for providing the best services for many event planners and individuals. Our dedicated and committed team of event coordinators would love to help you plan your perfect reception in Beaufort.




Celebrate with Our Mother’s Day Brunch

Mother’s Day Brunch Looking for a great place to treat mom this Mother’s Day? Our delicious Mother's Day Brunch Buffet is sure to please! Enjoy a variety of brunch favorites while taking in amazing views of the Beaufort River outside on our River Deck, or seated in a quiet, cozy table indoors. Bring mom and the whole family to Panini’s on the Waterfront this Sunday!   Read More →

Vote Panini's - Beaufort Gazette Reader's Choice Awards

Beaufort Gazette Reader’s Choice Awards Panini's on The Waterfront is proud to be a part of this fine Beaufort, Lowcountry community. We truly love where we live and work and take pride in serving our local Beaufort residents and visitors to the very best of our ability. We're asking for your vote again in this year’s Beaufort Gazette Reader’s Choice Awards!   Read More →