• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza


Live Music

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, delicious panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.


In addition to great dining, Panini's on The Waterfront is very proud to call itself one of the best banquet facilities in Beaufort South Carolina. We are well-known for providing the best services for many event planners and individuals. Our dedicated and committed team of event coordinators would love to help you plan your perfect reception in Beaufort.




Restaurant Week Special 3 Course Menu

Restaurant Week Grab your appetite and enjoy Restaurant Week in Beaufort. Come celebrate our local food scene with a delicious 3 course menu option at Panini's. This dine-in only deal includes choice of appetizer, soup, or salad plus pizza and desert - serves 2 people - only $29! Valid January 11 - 21 and may not be combined with any other offer. Beverages and tax not included. See menu for details.  Read More →

Good Eats in Downtown Beaufort Begins with Panini’s

Dining Room When you head into Beaufort, you are probably expecting an old-fashioned little place, located in the historic district. However, what you get is far more amazing and scrumptious. Beaufort is home to several restaurants, but Panini’s on the Waterfront takes the proverbial cake as one of the best. Sure, a panini is a delicious sandwich, and this restaurant serves those. But they also serve up homemade sauces, fresh-baked pizzas, salads, appetizers, and a bunch of delicious sides and desserts to tantalize your taste buds.  Read More →