• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza


Live Music

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, delicious panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.


In addition to great dining, Panini's on The Waterfront is very proud to call itself one of the best banquet facilities in Beaufort South Carolina. We are well-known for providing the best services for many event planners and individuals. Our dedicated and committed team of event coordinators would love to help you plan your perfect reception in Beaufort.




Guest Music Artist, Patience Clements at Panini's

Special Jazz Night Patience ClementsJoin us this Thursday night, May 24th, for a special performance by Guest Music Artist, Patience Clements. We invite you to unwind and dine as you enjoy her lively music along with drinks and the super friendly crowd at Panini's. No reservations required.   Read More →

Tasty Reviews of Beaufort’s Favorite Restaurant

tasty Beaufort dining Are you a self-proclaimed foodie? Is there nothing better than trying something new, delicious, and fresh-made? If you love good food and an amazing atmosphere, take a chance on Paninis’ on the Waterfront—one of Beaufort’s best restaurants and a favorite among locals and travelers alike.   Read More →