• Old Beaufort Bank Building
  • shrimp and seafood
  • downtown dining
  • fresh beaufort seafood
  • delicious dining
  • brick oven pizza

We're Open with NEW Covid-19 precautions!

Join us inside or on the River Deck! Our facility and team are taking additional safety precautions per SCDHEC guidelines.

Located in the historic Beaufort bank building, Panini’s is a delightful blend of old world Italian charm and new world cuisine. Serving unique and crispy stone-baked pizza, delicious panini sandwiches, hoagies, large salads, inventive pastas, and fresh local seafood - all made with a Mediterranean flare. You'll also love our famous homemade Italian desserts. We feature a full bar, both indoors and outside, and the restaurant overlooks Beaufort's Waterfront Park. See our complete menu here.

In addition to great dining, Panini's on The Waterfront is very proud to call itself one of the best banquet facilities in Beaufort South Carolina. We are well-known for providing the best services for many event planners and individuals. Our dedicated and committed team of event coordinators would love to help you plan your perfect reception in Beaufort.


Open with NEW Extensive Covid-19 Safety Measures

Palmetto Priority We are OPEN following some recent changes to our operation. We have taken the last few weeks to make extensive improvements and facility renovations to help guard against Covid-19 throughout our property. This includes a new UV Sanitizing System installed in all HVAC units to kill all airborne pathogens and contaminants. The Panini's Staff is also committment to the Palmetto Priority Program operating safely under SCDHEC guidelines. Guests are encouraged to join us inside, or on the River Deck overlooking Henry C. Chambers Waterfront Park for lunch, dinner, and drinks.  Read More →

Exploring and Having Dinner in Downtown Beaufort

Shrimp and GritsOften called sophisticated, with an old-world grace that charms locals and travelers alike, Downtown Beaufort is a historic destination that sits at the heart of South Carolina’s rich history. The second city to be founded in South Carolina, after Charleston, the Downtown Beaufort area coalesces fascinating Southern history, hospitality, and architecture, with a dash of contemporary glamour. The waterside of Downtown Beaufort are situated alongside several shops and places to explore, but most travelers and locals stroll the sidewalks to find somewhere new and delicious to dine.  Read More →